Intended for in vitro diagnostic (IVD) use. Epithelial antigen is a cell surface glycoprotein and is broadly distributed in epithelial cells and displays a highly conserved expression in carcinomas. Epithelial antigen has been shown to play an important role as a tumor cell marker in lymph nodes form patients with esophageal carcinoma. Epithelial antigen can be used to distinguish between basal cell and basosquamous carcinomas and squamous cell carcinomas of the skin.
- i) Beer et al. Histopathol 37: 218, 2000.
- ii) Carella et al. Am J Surg Pathol 25: 43, 2001.
iii) Hosch et al. Cancer Res 15: 60: 6836, 2000.
- iv) Momburg et al. Cancer Res 47: 2883, 1987.