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What is large format processing?

Large format tissue processing is a technique for histology laboratories to process larger pieces of tissue using the same instruments as those for standard tissue processing. Studies have shown that large format processing saves time and money and provides pathologists a better view of the case instead of piecing it back together on multiple slides.1, 2

Pathflow Supa Mega cassettes are almost three times the size of a standard cassette and can fit that much more tissue. With large format histology, pathologists are able to see more of the tissue at once, allowing better examination of whole tissue sections and margins. They're available in standard, slim, and SupaMega Mothership sizes.

PathFlow SupaMega Mothership Cassettes use an innovative docking bay for the majority of standard-sized tissue processing cassettes printed with ID bar codes and/or test information. This enables the specimen to be entered onto an LIS, guaranteeing accurate and reliable tracking.

Is large format right for your lab?

Large format processing is used to allow a whole organ section to be studied on one slide instead of multiple slides. It can be used with many tissue types such as bone, bowel, brain, breast, kidney, liver, lung, pancreas, prostate, skin, and thyroid, and is excellent to use in clinical labs where multiple cases of these tissue types are processed, Urology labs for prostates, or veterinary labs where vocal cords or jaws are studied.

Improved care

The ability to see tumor profile in large sections at once eliminates the mental jigsaw puzzle of piecing together cases from multiple slides.

Compatible 

No need to change processing or staining machines. Only the addition of a clamp is needed for the microtome.
 

Time savings

No further dissection required to fit into smaller cassettes. Eliminates the need of pathologists to switch between multiple slides.

Cost savings

Reduced number of slides to be processed and cut, saving both time and processing costs in reagents, stains and slides.

Download a free e-book with everything you need to get started with large format processing.

  • Protocols
  • Workflow and equipment modifications
  • Use cases
  • Product lists

Designed for you. Made by us.
SupaMega cassettes are manufactured in the StatLab Newtown, Wales manufacturing center of excellence.

StatLab is here to help you get started.

For standard large format processes, equipment already in your lab can be utilized; all that is needed to get started are large format slides, coverslips, cassettes, base molds, slide rack adaptors, and a universal microtome clamp.

Still need help? Review large format application bulletin here.

Or contact our expert technical support team. Call 1-800-442-3573 X5 or email[email protected]

PathFlow SupaMega Cassettes
100/box

PathFlow SupaMega Slim Cassettes
100/box

PathFlow SupaMega Mothership
100/box

"We routinely utilize whole mounts for prostates, melanoma, breast lumpectomies, and even some brain autopsies. Having the ability to visualize the complete margins negates the need to mentally reconstruct the tissue and permits the use of zero magnification photographs. This is an extremely useful tool in our laboratory. It allows us to demonstrate tumor features and growth patterns, all in relation to the margins."

JEREMY JOHNSTON, LABORATORY MANAGER, AVERO DIAGNOSTICS (FORMERLY NORTHWEST PATHOLOGY)

Looking for an SDS or Instructions for Use (IFU)? 

On your team.

HERE TO HELP

Call our friendly Customer Service team with any questions about products or ordering: 1‑800‑442‑3573

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Order by 12pm CST for same day shipping from coast to coast distribution centers

QUALITY GUARANTEED

Many products are manufactured right here in our state of the art facility with ISO 13485 standards for quality you can rely on