Mouse Monoclonal, RTU. Intended for in vitro diagnostic (IVD) use. PTEN is a protein that, in humans, is encoded by the PTEN gene. PTEN is one of the most commonly lost tumor suppressors in human cancer. Frequent genetic inactivation of PTEN occurs in glioblastoma, endometrial cancer, and prostate cancer, and reduced expression is found in many other tumor types such as lung and breast cancer. In breast and prostate cancer, loss of PTEN expression has been shown to corelate positively with advanced stage.
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