NEW Latex and Nitrile Gloves Back In Stock! Unlimited order quantities.

p53, Clone DO-7, 15mL

SKU #: QHD-MM120-15
You must be logged in to add to favorites.
p53, Clone DO-7, 15mL is available to buy in increments of 1
Mouse Monoclonal, RTU. Intended for in vitro diagnostic (IVD) use. Anti-p53 tumor suppressor protein antibody recognizes a 53 kDa phosphoprotein, identified as a p53 suppressor gene product. It reacts with the mutant as well as wild typep53. Positive nuclear staining with this antibody has been shown to be a factor in breast carcinoma, lung carcinoma, colorectal carcinoma, urothelial carcinoma, and ependymoma. Anti-p53 positivity has also been used to differentiate uterine serous carcinoma from endometrioid carcinoma, as well as a marker for intratubular germ cell neoplasia. References 1. Dabbs DJ. Diagnositc Immunohistochemistry. Third Edition. Saunders. 2006. 2. Mayall FG, et al. P-53 immunostaining in the distinction between benign and malignant mesothelial proliferations using formalin-fixed paraffin sections. J Pathol. 1992; 168:377-81. 3. Caffo O, et al. Prognostic value of p21(WAF1) and p53 expression in breast carcinoma: an immunohistochemical study in 261 patients with long-term follow-up. Clin Cancer Res.1996; 2:1591-9. 4. Bebenek M, et al. Prospective studies of p53 and c-erbB-2 expression in relation to clinicopathological parameters of human ductal breast cancer in the second stage of clinical advancement. Anticancer Res. 1998; 18:619-23. 5. Midulla C, et al. Immunohistochemical expression of p53, nm23-HI, Ki67 and DNA ploidy:correlation with lymph node status and other clinical pathologic parameters in breast cancer. Anticancer Res. 1999; 19:4033-7. 6. Van den Berg FM, et al. Detection of p-53 overexpression in routinely paraffin-embedded tissue of human carcinomas using a novel target unmasking fluid. Am J Pathol. 1993;142:381-5. 7. Zen ZS, et al. p53 nuclear overexpression: an independent predictor of survival in lymph node--positive colorectal cancer patients. J Clin Oncol. 1994; 12:2043-50. 8. Korshunov A, et al. Immunohistochemical markers for intracranial ependymoma recurrence. An analysis of 88 cases. J Neurol Sci. 2000; 177:72-82.
More Information
Pack Size Each

On your team.


Order by 12pm CST for same day shipping from coast to coast distribution centers


Many products are manufactured right here in our state of the art facility with ISO 13485 standards for quality you can rely on

© 2019-2021 SLMP, LLC, DBA StatLab Medical Products. All Rights Reserved.