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PathFlow Threaded Cassettes

Threaded cassettes are simple to load, but they are different than taped. Discover the benefits for your lab and the environment along with best tips for use.

Why threaded instead of taped cassettes?

Threaded cassettes reduce environmental impact.
Since StatLab switched to cardboard threaded cassettes at our Wales (CellPath) facility in 2021, we've used over 384 miles of cardboard threads instead of plastic tape or nylon threads​, which end up taking space in landfills. That's equivalent to tape stretching from Indianapolis, Indiana, to Columbus, Ohio, and back again--with miles to spare! Customers across Europe and the United States have successfully loaded over 1.3 million stacks of threaded cassettes into automated cassette printers over the past three years.

Threaded cassettes prevent jamming from tape residue. 
Taped cassettes can leave sticky residue on cassettes, which can lead to jams. To combat this, some laboratories remove the tape residue with an alcohol or xylene wipe prior to use, adding time to their workflow, in addition to cleaning the metal plate inside the IPC printer when this occurs. Cardboard threads leave no trace of residue, eliminating this step.

Tips for using threaded cassettes instead of taped:

  • Lay the thread of cassettes on a flat surface to align cassettes and prepare for loading before picking up by the top and bottom to stabilize.
  • Hold the cassettes directly above the hopper with one hand supporting the bottom of the thread. Do not hold the cassettes at an angle.
  • After loading the cassettes down into the hopper, place one finger on the top of the cassette stack to hold in place, while pulling up on the cardboard thread with the other hand. 
  • Dispose of the thread, which will naturally decompose in a landfill. 

Tips for loading cassettes into Sakura or Primera automated cassette printers:

Tips for loading cassettes into PiSmart automated cassette printers:

Need to return a product?

Initiate a return using the Return Merchandise Authorization (RMA) form below within 60 days of purchase, and unopened products can be returned for full credit on your account.

How is shipping handled? If you received the product in error, StatLab will pay return shipping fees. If you changed your mind after you purchased a product, you will pay return shipping fees.



  • Without receiving an RMA, we can’t quickly restock and issue your account a credit.
  • If items are returned without this information, a 25% restocking fee for each item returned will be applied. 
  • Standard return policy is 60 days.
  • If a product is defective, the return policy is extended to 120 days.  

The first step is simple. Fill out the RMA form below, including as much information as possible.

Once notification is received, you will be contacted by Customer Service to coordinate next steps or return shipping.

When the product is received, you will see a credit on your account within 30 days. 

Is large format right for your lab?

Large format processing is used to allow a whole organ section to be studied on one slide instead of multiple slides. It can be used with many tissue types such as bone, bowel, brain, breast, kidney, liver, lung, pancreas, prostate, skin, and thyroid, and is excellent to use in clinical labs where multiple cases of these tissue types are processed, Urology labs for prostates, or veterinary labs where vocal cords or jaws are studied.

Improved care

The ability to see tumor profile in large sections at once eliminates the mental jigsaw puzzle of piecing together cases from multiple slides.


No need to change processing or staining machines. Only the addition of a clamp is needed for the microtome.

Time savings

No further dissection required to fit into smaller cassettes. Eliminates the need of pathologists to switch between multiple slides.

Cost savings

Reduced number of slides to be processed and cut, saving both time and processing costs in reagents, stains and slides.

Download a free e-book with everything you need to get started with large format processing.

  • Protocols
  • Workflow and equipment modifications
  • Use cases
  • Product lists

Designed for you. Made by us.
SupaMega cassettes are manufactured in the StatLab Newtown, Wales manufacturing center of excellence.

StatLab is here to help you get started.

For standard large format processes, equipment already in your lab can be utilized; all that is needed to get started are large format slides, coverslips, cassettes, base molds, slide rack adaptors, and a universal microtome clamp.

Still need help? Review large format application bulletin here.

Or contact our expert technical support team. Call 1-800-442-3573 X5 or email[email protected]

PathFlow SupaMega Cassettes

PathFlow SupaMega Slim Cassettes

PathFlow SupaMega Mothership

Universal Clamp
Sold Individually

SupaMega Base Molds

SupaMega Claritex Slides

"We routinely utilize whole mounts for prostates, melanoma, breast lumpectomies, and even some brain autopsies. Having the ability to visualize the complete margins negates the need to mentally reconstruct the tissue and permits the use of zero magnification photographs. This is an extremely useful tool in our laboratory. It allows us to demonstrate tumor features and growth patterns, all in relation to the margins."


Order PathFlow SupaMega online or call 1-800-442-3573. 

On your team.


Call our friendly Customer Service team with any questions about products or ordering: 1‑800‑442‑3573


Order by 12pm CST for same day shipping from coast to coast distribution centers


Many products are manufactured right here in our state of the art facility with ISO 13485 standards for quality you can rely on