Cytokeratin 7, Clone OV-TL12/30
Mouse Monoclonal, RTU. Intended for in vitro diagnostic (IVD) use. Anti-cytokeratin 7 (CK7) reacts with proteins that are found in most ductal, glandular, transitional, and biliary duct epithelial cells. CK7 is a common marker of primary lung adenocarcinomas (almost all cases) with a lower specificity since it is also observed in other primary lung carcinomas and non-pulmonary carcinomas. CK7 is also useful in the differential diagnosis of ovarian neoplasms. CK7 does not recognize intermediate filament proteins. References 1. Jerome MV, et al. Expression of TTF-1 and Cytokeratins in Primary and Secondary Epithelial Lung Tumours: Correlation with Histological Type and Grade. Histopathology. 2004; 45:125-34. 2. McCluggage WG, et al. Metastatic Neoplasms Involving the Ovary: a Review with an Emphasis on Morphological and Immunohistochemical Features. Histopathology. 2005; 47:231-247.