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Cytokeratin AE3 (Basic), Clone AE3

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Grouped product items
Product Name Qty
Cytokeratin AE3 (Basic), Clone AE3, 10mL
SKU #: MM50-10 EA
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Cytokeratin AE3 (Basic), Clone AE3, 6mL (Manual Use)
SKU #: MM50-6 EA
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Cytokeratin AE3 (Basic), Clone AE3 is available to buy in increments of 1

Mouse Monoclonal. Intended for in vitro diagnostic (IVD) use. This high molecular weight antibody can recognize all basic keratins, and so is a broadly reactive antibody that stains most epithelia and their neoplasms. Members of the acidic and basic subfamilies are found together in pairs, and since each epithelium contains at least one acidic and one basic keratin, this antibody can be used to observe the distribution of keratin-containing cells in normal epithelia and neoplasms derived from these epithelia. References 1. Tyler CR. Immunoperoxidase techniques: practical and theoretical aspects. Arch Pathol Lab Med. 1978; 102:113-21. 2. Weiss RA, et al. Monoclonal antibody analysis of keratin expression in epidermal diseases: a 48-and 56-kDlton keratin as molecular markers for hyperproliferative keratinocytes. J Cell Biol. 1984; 98:1397-406. 3. Lopez-Beltran A, et al. Lymphoepithelioma-like carcinoma of the urinary bladder: a clinicopathologic study of 13 cases. Virchows Arch. 2001; 438:552-7. 4. Nelson WG, et al. The 50- and 58-kDlton keratin classes as molecular markers for stratified squamous epithelia: cell culture studies. J Cell Biol. 1983; 97:244-51. 5. Sun TT, et al. Monoclonal antibody studies of mammalian epithelial keratins: a review. Ann N Y Acad Sci. 1985; 455:307-29

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