Rabbit Polyclonal, RTU. Intended for in vitro diagnostic (IVD) use. Calretinin is a 29-kDa calcium-binding protein thought to play a role in the cell cycle. Anti-calretinin labels mesothelial and Leydig cells under normal and neoplastic conditions. Anti-calretinin has been shown to be useful in differentiating mesothelioma from adenocarcinomas of the lung and other sources. References 1. Rogers JH. Calretinin: a gene for a novel calcium-binding protein expressed principally in neurons. J Cell Biol. 1987; 105:1343-53. 2. Doglioni C, et al. Calretinin: a novel immunocytochemical marker for mesothelioma. Am J Surg Pathol. 1996; 20:1037-46. 3. Augusto D, et al. Calretinin: a valuable marker of normal and neoplastic Leydig cells of the testis. Appl Immunohistochem Mol Morphol. 2002; 10:159-62. 4. Barberis MC, et al. Calretinin. A selective marker of normal and neoplastic mesothelial cells in serous effusions. Acta Cytol. 1997; 41:1757-61.