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CD10, Clone 56C6, 15mL

SKU #: QHD-MM14-15
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Mouse Monoclonal, RTU. Intended for in vitro diagnostic (IVD) use. CD, common acute lymphoblastic leukemia antigen, is expressed by a subset of T follicular helper cells. CD10 has a direct role in cell growth and apoptosis and has been implicated in tumor cell proliferation. CD10 expression has been reported in a variety of tissues, including renal cell carcinoma, hepatocellular carcinoma, and follicular lymphoma. References 1. Maguer-Satta V, et al. Concise review: neutral endopeptidase (CD10): a multifaceted environment actor in stem cells, physiological mechanisms, and cancer. Stem Cells. 2011; 29:389-96. 2. Laurent C, et al. A novel subset of T-helper cells: follicular T-helper cells and their markers. Haematologica. 2010; 95: 356-8. 3. Onak NK, et al. CD10 expression in urothelial bladder carcinomas: staining patterns and relationship with pathologic parameters. Turk J Med Sci. 2010; 40:177-84. 4. Chu P, et al. Paraffin-section detection of CD10 in 505 nonhematopoietic neoplasms. Am J Clin Pathol. 2000; 113: 374-82. 5. Swerdlow S, et al. WHO classification of tumours of hematopoietic and lymphoid tissues. 4th edition. 2008. P. 220,233,255,265,309.

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